General Information

  • ID:  hor003221
  • Uniprot ID:  NA
  • Protein name:  Leu-Val-Val-hemorphin-7
  • Gene name:  NA
  • Organism:  NA
  • Family:  Opioid neuropeptide precursor family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  LVVYPWTQRY
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003221_AF2.pdbhor003221_ESM.pdb

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Physical Information

Mass: 148525 Formula: C65H93N15O15
Absent amino acids: ACDEFGHIKMNS Common amino acids: VY
pI: 9.17 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: -16 Boman Index: -798
Half-Life: 5.5 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 97
Instability Index: -1919 Extinction Coefficient cystines: 8480
Absorbance 280nm: 942.22

Literature

  • PubMed ID:  14499287
  • Title:  Kinetic-controlled Hydrolysis of Leu-Val-Val-hemorphin-7 Catalyzed by Angiotensin-Converting Enzyme From Rat Brain